Tunodafil Hydrochloride Application Scope

Tunorfinib (Taituotuo®) is an oral medication used for the treatment of erectile dysfunction (ED) in adult males, improving erectile function by increasing penile blood flow.

Tunodafil Hydrochloride Characteristics

Ingredients: Tunorfinib Hydrochloride (active ingredient)
Properties: White to off-white film-coated tablet for oral administration
Packaging Specification: 50 mg × 1 tablet (typical pack sizes 1/2/4 tablets per box, depending on market)
Storage: Store below 25 °C in a cool, dry place; keep in original blister to protect from moisture and light
Expiry Date: 24 months from manufacturing date (see carton for exact date)
Executive Standard: Complies with national drug standards (YBZ / local pharmacopoeia)
Approval Number: National Medical Products Administration (NMPA) approval — see package insert for exact number
Date of Revision: See the latest prescribing information
Manufacturer: Yangtze River Pharmaceutical Group Co., Ltd. (Jiangsu, China)

Guidelines for the Use of Taituotuo

Dosage and Administration:
- Recommended Dose: 50 mg orally as needed, approximately 1 hour before sexual activity; adjust dose based on efficacy and tolerability
- Administration: Swallow the tablet whole with water; can be taken with or without food
- Missed Dose: Not applicable for on-demand dosing; do not exceed recommended frequency (once per day)
Adverse Reactions:
- Common Adverse Reactions:
  - Headache
  - Facial flushing
  - Nasal congestion
  - Dyspepsia
- Serious Adverse Reactions:
  - Hypotension (rare)
  - Priapism (prolonged erection >4 h — seek medical help)
  - Sudden vision or hearing loss (very rare, report immediately)
Contraindications:
- Concurrent nitrate therapy (risk of severe hypotension)
- Severe cardiovascular disorders where sexual activity is inadvisable
- Known hypersensitivity to tunorfinib or any excipient
Precautions:
- Please be sure to use caution in patients with hepatic or renal impairment.
- Monitor for cardiovascular risk before initiation.
- Avoid alcohol overuse (may increase hypotension risk)
- Not recommended in patients <18 years

Tunodafil Hydrochloride Interactions

Nitrates: Contraindicated due to risk of profound hypotension
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): may increase drug levels → consider lower dose
CYP3A4 inducers (e.g., rifampin): may reduce efficacy
Antihypertensives: Additive BP-lowering effect — monitor

Note:

If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from DengYue Medicine.
This content is for reference only. Prescription drugs must be used under a doctor’s guidance and purchased from authorized sources.