Youshiying (Fluocinolone Acetonide Intravitreal Implants) – NIU-PS | HongKong DengYue Medicine

Fluocinolone Acetonide Intravitreal Implants Application Scope

Treatment of chronic non-infectious uveitis affecting the posterior segment of the eye (NIU-PS) and diabetic macular edema (DME) in patients who have been previously treated with a course of corticosteroids and did not have a clinically significant rise in intraocular pressure.

Fluocinolone Acetonide Intravitreal Implants Characteristics

• Ingredients: Active ingredient: Fluocinolone acetonide.

• Properties: Fluocinolone acetonide is a synthetic corticosteroid with anti-inflammatory properties.

• Packaging Specification: Available as a non-bioerodible intravitreal implant containing 0.19 mg fluocinolone acetonide.

• Storage: Store at 15°C to 30°C (59°F to 86°F).

• Expiry Date: Not specified; refer to the product packaging for the specific expiry date.

• Executive Standard: Complies with the United States Pharmacopeia (USP) standards.

• Approval Number: NDA 201923.

• Date of Revision: December 2021.

• Manufacturer: Alimera Sciences, Inc.

Guidelines for the Use of Fluocinolone Acetonide Intravitreal Implants

• Dosage and Administration: Administered as a single intravitreal injection under aseptic conditions.

  • Recommended Dose: One implant containing 0.19 mg fluocinolone acetonide.

  • Administration: Implant is injected directly into the vitreous cavity using a preloaded applicator.

  • Missed Dose:​ If a dose is missed, administer as soon as possible.

• Adverse Reactions:

  • Common Adverse Reactions: Increased intraocular pressure, cataract formation, eye pain, and blurred vision.

  • Serious Adverse Reactions: Endophthalmitis, retinal detachment, and vitreous hemorrhage

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• Contraindications:

  • Active ocular or periocular infections.

  • Hypersensitivity to fluocinolone acetonide or any component of the implant.

• Precautions:

  • Monitor intraocular pressure regularly during treatment.

  • Use with caution in patients with a history of glaucoma.

  • Sterility must be maintained during administration to prevent infection.

Fluocinolone Acetonide Intravitreal Implants Interactions

• No significant drug interactions have been reported.

 

Note:

• If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from DengYue Medicine.
•  This content is for reference only. Prescription drugs must be used under a doctor’s guidance and purchased from authorized sources.