Syprine Trientine Hydrochloride Tablets Application Scope

Trientine Hydrochloride Tablets are indicated for the treatment of Wilson’s disease in patients who cannot tolerate penicillamine. Wilson’s disease is characterized by the body’s inability to eliminate excess copper, leading to its accumulation, which can cause liver and neurological damage.

Syprine Trientine Hydrochloride Tablets Characteristics

Ingredients:Each tablet contains trientine hydrochloride as the active ingredient.
Properties:Trientine hydrochloride is a chelating agent that binds to excess copper, facilitating its excretion from the body.
Specification:Tablets are available in 300 mg strength.

Packaging Specification:

Storage: Store at controlled room temperature, away from moisture and light.
Effective Period: Refer to the product packaging for the expiration date.
Approval Number: Refer to the regulatory authority’s approval number on the product packaging.
Manufacturer: Refer to the product packaging for manufacturer details.

Guidelines For The Use Of Syprine Trientine Hydrochloride Tablets

Dosage and Administration: The recommended starting dose for adults is 750 mg per day, divided into two to four doses. The maximum daily dose should not exceed 2,000 mg. Pediatric dosing varies; consult prescribing information for details. It is important to take Trientine Hydrochloride Tablets on an empty stomach, at least one hour before meals or two hours after meals, and at least one hour apart from any other drug, food, or milk. Swallow the tablets whole with water; do not open or chew them.
Adverse Reactions: Common side effects include nausea, especially when starting treatment, skin rash, and inflammation of the duodenum or large bowel, causing pain and diarrhea.

Medication Limitations

Contraindications: Trientine Hydrochloride Tablets are contraindicated in patients with known hypersensitivity to trientine or any of its components.
Precautions: Use with caution in patients with iron deficiency; if iron supplementation is necessary, administer it at least two hours apart from Trientine Hydrochloride Tablets. Regular monitoring of serum copper levels is recommended to avoid over-chelation.

Syprine Trientine Hydrochloride Tablets Interactions

Drug Interactions: Trientine may reduce iron absorption; conversely, iron supplements can decrease the effectiveness of trientine. Administer iron supplements and Trientine Hydrochloride Tablets at least two hours apart.

Note:

If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from HongKong DengYue Medicine. It is only for internal discussion among medical staff and does not serve as a basis for medication. For specific medication guidelines, please consult the attending physician.