Sulbactam Durlobactam Application Scope

Sulbactam Durlobactam are used for the treatment of serious bacterial infections, including hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP), caused by Acinetobacter baumannii-calcoaceticus complex.

Sulbactam-Durlobactam Characteristics

Ingredients:
- Sulbactam: A beta-lactamase inhibitor
- Durlobactam: A novel beta-lactamase inhibitor
Properties:
- Sulbactam/Durlobactam are both beta-lactamase inhibitors that work by inhibiting bacterial enzymes that would otherwise degrade beta-lactam antibiotics, thereby enhancing their antimicrobial activity.
Specification:
- Sulbactam-Durlobactam is available for intravenous injection in a combination form with 1 gram of Sulbactam and 1 gram of Durlobactam in each vial.
Packaging Specification:
- Packaging: Each box contains 3 vials: 1 vial containing 1g of Sulbactam and 2 vials containing 0.5g of Durlobactam each.
Storage:
- Store in a cool, dry place, away from direct sunlight. Refer to packaging for specific storage conditions.
Expiry Date:
- The expiry date is indicated on the packaging.
Executive Standard:
- The product adheres to the relevant pharmaceutical standards and guidelines for injectable drugs.
Approval Number:
- The approval number is listed on the packaging.
Date of Revision:
- Refer to packaging for the most recent revision date.
Manufacturer:
- La Jolla Pharmaceutical Company

Guidelines For The Use Of Sulbactam Durlobactam

Dosage and Administration: The recommended dose is 1 gram of Sulbactam and 1 gram of Durlobactam administered intravenously every 6 hours, with an infusion time of 3 hours per dose.

Adverse Reactions: Common side effects may include diarrhea, anemia, and hypokalemia. Please consult the prescribing information for a complete list of potential adverse reactions.

Contraindications: Durlobactam Sulbactam is contraindicated in patients who are allergic to sulbactam durlobactam, Durlobactam, or other beta-lactam antibiotics.

Precautions: Renal function should be monitored during treatment. Dose adjustments may be necessary in patients with impaired kidney function.

Sulbactam Durlobactam Interactions

Drug Interactions: Caution should be exercised when used concurrently with other nephrotoxic drugs or those that affect renal function. Monitoring for potential drug-drug interactions is recommended.

Note:

If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from HongKong DengYue Medicine.
It is only for internal discussion among medical staff and does not serve as a basis for medication. For specific medication guidelines, please consult the attending physician.