Metreleptin Application Scope

Metreleptin is used together with diet to treat complications caused by leptin deficiency in people who have lipodystrophy (also called fat redistribution). It is not for use in people who are obese or have lipodystrophy caused by HIV or AIDS.

Characteristics

Ingredients: Metreleptin is a human recombinant leptin protein.
Properties: A recombinant form of the human hormone leptin, which is involved in the regulation of body weight, energy expenditure, and metabolism.
Specification: 11.3 mg powder for injection.
Packaging Specification: Each box contains 10 vials, each containing 11.3 mg of Metreleptin.
Storage: Unmixed vials should be stored in the refrigerator, protected from light, and not frozen. Mixed solutions should be used within 3 days (if mixed with Bacteriostatic Water for Injection) or immediately (if mixed with Sterile Water for Injection).
Expiry Date: Check the label on the vial.
Executive Standard: Approved by relevant regulatory authorities.
Approval Number: FDA Approval Number: BLA 125390
Date of Revision: March 2024
Manufacturer: Chiesi Farmaceutici S.p.A.

Guidelines For The Use Of Metreleptin

Dosage and Administration: Dosage is based on weight, especially in children and teenagers. It is usually given once daily, subcutaneously, at any time of day, with or without food.

Adverse Reactions: Common side effects may include headache and stomach pain. In some people, it can trigger an immune response, leading to less effectiveness or certain side effects.

Contraindications: Do not use if allergic to metreleptin. Not for treating obesity unrelated to leptin deficiency.

Precautions: Inform your doctor if you have certain medical conditions, are pregnant or plan to become pregnant, or are breastfeeding.

Interactions

Drug Interactions: Inform your doctor of all medications you are taking, as metreleptin may interact with other drugs.

Note:

If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from DengYue Medicine.
It is only for internal discussion among medical staff and does not serve as a basis for medication. For specific medication guidelines, please consult the attending physician.