Aggrastin α Application Scope

Indicated for adult patients with non-myeloid malignancies undergoing chemotherapy that is likely to cause febrile neutropenia, to reduce the incidence of infections manifested as febrile neutropenia.

Aggrastin α Characteristics

Ingredients: Recombinant human granulocyte colony-stimulating factor (G-CSF) α fused with human serum albumin (HSA).
Properties: A fourth-generation long-acting G-CSF utilizing HSA fusion technology to extend the half-life in the body, reducing dosing frequency and improving patient compliance.
Packaging Specification: 20 mg per vial.
Storage: Store at 2–8°C, protected from light.
Expiry Date: Refer to the packaging label.
Executive Standard: Chinese Pharmacopoeia 2020 Edition.
Approval Number: National Drug Approval No. H20250031.
Date of Revision: May 2025.
Manufacturer: Qilu Pharmaceutical Co., Ltd.

Guidelines for the Use of Mailisheng

Dosage and Administration:
- Recommended Dose: 500 μg/kg, administered subcutaneously on the third day after the end of the chemotherapy cycle.
- Administration: Subcutaneous injection.
- Missed Dose: If a dose is missed, administer as soon as possible. Consult a healthcare professional for guidance.
Adverse Reactions:
- Common Adverse Reactions:
  - Injection site reactions
  - muscle pain
  - fatigue
- Serious Adverse Reactions:
  - Allergic reactions
  - chest pain
  - difficulty breathing
Contraindications: Contraindicated in patients with known hypersensitivity to this product or its components.
Precautions:
- Assess the patient’s history of allergies to G-CSF-like drugs before use
- regularly monitor the injection site.

Aggrastin α Interactions

Currently, there is no specific data available regarding drug interactions.
During treatment with this product, avoid concurrent use with other G-CSF-like drugs to reduce the risk of adverse reactions.

Note:

If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from DengYue Medicine.
This content is for reference only. Prescription drugs must be used under a doctor’s guidance and purchased from authorized sources.