Letybo Application Scope

Letybo is an FDA-approved botulinum toxin type A injectable treatment designed to temporarily improve the appearance of moderate to severe glabellar lines (frown lines between the eyebrows) in adults.

letybo

Characteristics

Ingredients:
- LetibotulinumtoxinA-wlbg

Properties: Letybo is a neuromuscular blocking agent that inhibits acetylcholine release at the neuromuscular junction, leading to temporary muscle relaxation
Packaging Specification: Supplied as a white, freeze-dried powder in single-dose vials containing either 50 or 100 Units

Storage:
- Store unopened vials refrigerated at 2°C to 8°C (36°F to 46°F) in the original carton to protect from light
- Do not freeze
Expiry Date: Unopened vials have a shelf life of 3 years
Executive Standard: Approved under regulatory standards by agencies such as the FDA and TGA
Approval Number: FDA approval granted on February 29, 2024
Date of Revision: February 2024
Manufacturer: Hugel, Inc., Chuncheon, South Korea

Guidelines for the Use of Letybo

Dosage and Administration:
- Recommended Dose: 30 mg orally, taken twice weekly (with at least 72 hours between doses)
- Administration: Can be taken with or without food; no dietary restrictions (including grapefruit or dairy)
- Missed Dose: If a dose is missed, it should be taken within 12 hours of the scheduled time; otherwise, skip and resume the next scheduled dose

Adverse Reactions:
- Common side effects include headache and injection site reactions
- Serious adverse reactions may include hypersensitivity reactions, cardiovascular events, and symptoms related to the spread of toxin effects, such as dysphagia and respiratory difficulties.

Contraindications: Contraindicated in individuals with known hypersensitivity to any botulinum toxin preparation or any components of the formulation, and in those with infection at the proposed injection site.
Precautions:
- Use with caution in patients with pre-existing neuromuscular disorders, cardiovascular disease, or compromised respiratory function.
- The effects of botulinum toxin may spread beyond the injection site, leading to serious symptoms.

Interactions

Drug Interactions: Caution is advised when Letybo is administered concomitantly with aminoglycosides, anticholinergic agents, or other agents that interfere with neuromuscular transmission, as these may potentiate the effect of Letybo

Note:

If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from DengYue Medicine.
It is only for internal discussion among medical staff and does not serve as a basis for medication. For specific medication guidelines, please consult the attending physician.