Haidewei Calcitriol Soft Capsules | Hypophosphatemic Rickets

  • Generic Name/Brand Name:Calcitriol Soft Capsules/Haidewei
  • Indications:Hypophosphatemic Rickets
  • Dosage Form:oral administration 
  • Specification:0.25 mcg, 0.5 mcg, or 1 mcg

Haidewei Calcitriol Soft Capsules Application Scope

Haidewei Calcitriol Soft Capsules are used for the treatment of hypocalcemia and secondary hyperparathyroidism in patients with chronic kidney disease (CKD) and osteoporosis. It is also used to manage conditions such as rickets, osteomalacia, and as an adjunctive therapy for hypoparathyroidism. The calcitriol in these capsules acts by increasing calcium and phosphate absorption in the intestines and enhancing calcium resorption in the kidneys.

haidewei calcitriol capsules
haidewei calcitriol capsules

Haidewei Calcitriol Soft Capsules Characteristics

  • Ingredients:
    • Active ingredient: Calcitriol (1,25-dihydroxyvitamin D3)
    • Excipients: May include soybean oil, gelatine, glycerol, and other stabilizers.
  • Properties:Calcitriol is the active form of vitamin D3, crucial for calcium homeostasis and bone metabolism. It helps regulate calcium and phosphate levels in the blood and supports normal bone mineralization.
  • Specification:Typically available in soft gel capsules containing 0.25 mcg, 0.5 mcg, or 1 mcg of calcitriol per capsule.
  • Packaging Specification:
  • Storage:Store in a cool, dry place, typically below 25°C (77°F), away from light.
  • Expiry Date:Typically 2–3 years from manufacturing (check packaging for exact expiry).
  • Executive Standard:Follows the pharmaceutical standards as defined by local or international regulatory bodies.
  • Approval Number:Approval numbers from NMPA (or relevant regulatory authority).
  • Manufacturer:Manufactured by Haidewei Pharmaceutical Co. Ltd. (or the relevant manufacturer).

Guidelines For The Use Of Haidewei Calcitriol Soft Capsules

Dosage and Administration:

  • Dosage depends on the specific condition being treated. Common starting doses range from 0.25 mcg to 1 mcg daily, which may be adjusted based on patient response and blood calcium levels.
  • Capsules should be taken orally, with or without food, as directed by the physician

Adverse Reactions:

  • Common side effects include hypercalcemia, nausea, headache, constipation, and fatigue.
  • Serious adverse reactions may include kidney stones, renal impairment, and cardiac arrhythmias due to hypercalcemia.

Medication Limitations

Contraindications:Hypercalcemia, vitamin D toxicity, severe renal impairment, or history of kidney stones.

Precautions:

    • Regular monitoring of calcium levels is necessary during treatment.
    • Caution in patients with heart disease or gastrointestinal disorders.

Haidewei Calcitriol Soft Capsules Interactions

Drug Interactions:

  • May interact with thiazide diuretics, phenytoin, barbiturates, and magnesium-containing medications.
  • Caution is needed when taken with calcium supplements or other vitamin D analogs, as this may increase the risk of hypercalcemia.

Note:

  • If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from HongKong DengYue Medicine, China Drug Import and Export Wholesaler.
    It is only for internal discussion among medical staff and does not serve as a basis for medication. For specific medication guidelines, please consult the attending physician.
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