Ganagliflozin Proline Tablets/Janagliflozin Application Scope

Janagliflozin is also named Ganagliflozin Proline Tablets, primarily used for managing Type 2 Diabetes Mellitus (T2DM) and has shown promise in improving blood glucose control for patients with inadequate glycemic control.

Ganagliflozin Proline Tablets Characteristics

Ingredients: The active ingredient in Janagliflozin is Janagliflozin itself, which is a sodium-glucose cotransporter-2 (SGLT-2) inhibitor.
Properties: Janagliflozin works by inhibiting the sodium-glucose cotransporter 2 (SGLT-2), which reduces glucose reabsorption in the kidneys and increases urinary glucose excretion, thus lowering blood glucose levels.
Specification: Available in 25 mg and 50 mg doses, typically in oral tablet form.
Packaging Specification: Usually packaged in blister packs containing 7 to 30 tablets.
Storage: Store in a cool, dry place below 25°C (77°F). Keep away from heat, humidity, and light.
Expiry Date: Refer to the specific packaging for the expiration date.
Executive Standard: The product must comply with the National Drug Standard (China) or similar regional standards.
Approval Number: Not publicly listed, may vary by region or regulatory body.
Date of Revision: Regular updates are issued by regulatory bodies as clinical trials progress.
Manufacturer: Shionogi & Co., Japan.

Guidelines For The Use Of Ganagliflozin Proline Tablets

Dosage and Administration:

Initial Dose: Typically, 25 mg once daily, which can be increased to 50 mg based on the patient’s condition and tolerance.
Administration: Should be taken orally with or without food.

Adverse Reactions:

Common Side Effects: Include urinary tract infections (UTIs), genital infections, increased urination, dehydration, and hypotension.
Serious Side Effects: Risk of diabetic ketoacidosis, acute kidney injury, and bone fractures.

Medication Limitations:

Not suitable for patients with Type 1 diabetes or diabetic ketoacidosis.
Caution in patients with renal impairment, as it may increase the risk of kidney problems.

Contraindications:

Contraindicated in patients with a history of diabetic ketoacidosis.
Pregnant and breastfeeding women should avoid using Janagliflozin.

Precautions:

Renal function should be monitored, especially in elderly patients and those with compromised kidney function.
Use with caution in patients with hypotension or volume depletion.

Ganagliflozin Proline Tablets Interactions

Drug Interactions:

Diuretics (e.g., thiazides): May enhance the risk of dehydration or hypotension.
Insulin or Insulin Secretagogues: Co-administration may increase the risk of hypoglycemia. Dose adjustments may be needed

Note:

If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from HongKong DengYue Medicine.
It is only for internal discussion among medical staff and does not serve as a basis for medication.
For specific medication guidelines, please consult the attending physician.