Elaprase Idursulfase | Mucopolysaccharidosis Type II | DengYueMedicine

Generic Name/Brand Name: Idursulfase/Elaprase
Indications: Mucopolysaccharidosis Type II
Dosage Form: Intravenous solution
Specification: Each vial contains 6 mg of idursulfase in 3 mL of solution (2 mg/mL)

Elaprase Idursulfase Application Scope

Elaprase Idursulfase is an enzyme replacement therapy indicated for the treatment of Hunter syndrome (Mucopolysaccharidosis II, MPS II), a rare genetic disorder caused by a deficiency of the iduronate-2-sulfatase enzyme. This deficiency leads to the accumulation of glycosaminoglycans (GAGs) in various tissues, resulting in progressive multi-system complications.

Elaprase Idursulfase Characteristics

Ingredients:Idursulfase beta (genetic recombination).
Properties:Hunterase is a sterile, nonpyrogenic, clear to slightly opalescent, colorless solution intended for intravenous infusion.
Specification:Each vial contains 6 mg of idursulfase beta in 3 mL of solution (2 mg/mL) at a pH of approximately 6.

Packaging Specification

Storage:Store under refrigeration at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Effective period: Refer to the expiration date on the vial.
Approval Number: Refer to local regulatory approval information.
Manufacturer:CANbridge Pharmaceuticals.

Guidelines For The Use Of Elaprase Idursulfase

Dosage and Administration: The recommended dosage regimen is 0.5 mg per kg of body weight administered once weekly as an intravenous infusion.
Adverse Reactions: Common adverse reactions include infusion-related reactions such as urticaria, pruritus, and cough.

Medication Limitations

Contraindications: Hypersensitivity to the active substance or any of the excipients.
Precautions: Monitor for signs of infusion-related reactions; consider premedication with antihistamines or corticosteroids.

Elaprase Idursulfase Interactions

Drug Interactions: No formal drug interaction studies have been conducted.

Note: If there is a new packaging for the drug, the new packaging shall prevail. The above information is sourced from HongKong DengYue Medicine. It is only for internal discussion among medical staff and does not serve as a basis for medication. For specific medication guidelines, please consult the attending physician.