TECVAYLI™ Approval Brings New Options For Multiple Myeloma Treatment

In October 2022, the U.S. Food and Drug Administration (FDA) granted accelerated TECVAYLI™ (teclistamab-cqyv) FDA approval, a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager.

For the treatment of adult patients with relapsed or refractory Tecvayli multiple myeloma who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.

Tecvayli Mechanism of Action

TECVAYLI™ is a first-in-class bispecific T-cell engager antibody that binds to both BCMA on myeloma cells and CD3 receptors on T-cells.

This dual binding redirects T-cells to target and eliminate BCMA-expressing myeloma cells, thereby exerting its antitumor effect.

Teclistamab Clinical Trials and Efficacy

In the pivotal clinical trial, TECVAYLI™ demonstrated an overall response rate of 61.8% among patients who had received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.

Tecvayli Side Effects

Common adverse reactions (≥20%) associated with Teclistamab-cqyv include cytokine release syndrome (CRS), neutropenia, anemia, thrombocytopenia, lymphopenia, infections, pyrexia, fatigue, musculoskeletal pain, nausea, headache, and diarrhea. Serious adverse reactions include infections, neurologic toxicity, and CRS.

Future Outlook

The approval of Tecvayli drug offers a new treatment option for patients with relapsed or refractory multiple myeloma, particularly those who have exhausted traditional therapies.

Ongoing studies aim to further evaluate its efficacy and safety in different patient populations and in combination with other therapies.

However, HK DengYue’s efforts to increase the affordability of the medicine are critical to ensuring that more patients benefit from it.

We welcome you to reach out to us to get Tecvayli price. DengYueMedicine is here to provide detailed medicine information, pricing, and support to ensure a smooth and reliable buying experience.

Feel free to contact us anytime to discuss your needs or ask any questions about the medicine.

Information from DengYueMed, China Drug Import and Export Wholesaler offers this information as a guide, not a substitute for professional medical advice. Consult your doctor before any treatment.