Introduction

Azathioprine Tablets, widely known under the brand Xinyi, is a versatile medication that plays a key role in managing several autoimmune diseases, chronic conditions, and organ transplant cases. As a trusted immunosuppressant, it helps regulate an overactive immune system.

In this comprehensive guide, we will break down the essential details of Azathioprine tablets: how they work, proper usage, and safety tips for patients.

What Are Azathioprine Tablets?

Azathioprine tablets contain 50mg of Azathioprine, a medication that helps suppress the immune system when it is overactive or misdirected. It belongs to a class of drugs known as immunosuppressants.

Common Uses of Azathioprine Tablets:

Autoimmune Diseases: Conditions where the immune system mistakenly attacks the body, including:
- Rheumatoid arthritis (joint inflammation)
- Systemic lupus erythematosus (SLE)
- Autoimmune hepatitis and primary biliary cirrhosis
Blood Disorders(Hematology): Treatment for chronic leukemia and idiopathic thrombocytopenic purpura (ITP).
Chronic Conditions: Such as ulcerative colitis and Crohn’s disease and Colorectal Cancer.
Organ Transplants: Prevents organ rejection by suppressing the immune response.

How do Azathioprine Tablets Work?

Azathioprine works by interfering with the DNA production of immune cells, slowing down their activity. This makes it highly effective for controlling inflammation and reducing immune responses that cause harm in autoimmune or chronic conditions.

Dosage and How to Take Azathioprine Tablets

General Guidelines:

The dosage depends on your condition and body weight. Always follow your doctor’s instructions.
Typically, the dose ranges from 1.5–4 mg/kg daily for autoimmune diseases and 2–5 mg/kg daily for organ transplants.

Tips for Taking Azathioprine:

Take the tablet with food or water to reduce stomach discomfort.
Do not crush or split the tablet.
If you miss a dose, take it as soon as you remember, unless it’s close to your next dose.

Safety Precautions and Side Effects Of Azathioprine Tablets

While Azathioprine is effective, patients need to be mindful of its side effects. Here’s what to watch for:

Common Side Effects:

Nausea or mild stomach upset
Skin rashes
Fatigue

Serious Side Effects:

Bone Marrow Suppression: Decreased blood cell counts, which may cause infections or fatigue.
Liver Toxicity: Regular liver function tests are necessary. Report yellowing of the skin or eyes immediately.
Increased Cancer Risk: Long-term use may slightly increase the risk of certain cancers, such as skin cancer or lymphoma.

Important Safety Tips:

Avoid prolonged sun exposure—use sunscreen to protect your skin.
Have routine blood tests to monitor your white blood cell count and liver function.
Pregnant or breastfeeding women should avoid Azathioprine as it may cause birth defects.

Drug Interactions to Consider:

Allopurinol (a gout medication): Can increase the toxicity of Azathioprine. If taken together, your doctor may need to adjust the dosage.
Inform your doctor of any other medications, including supplements.

Who Should Avoid Azathioprine?

Patients with severe liver disease.
Individuals allergic to Azathioprine or its components.
Pregnant or breastfeeding women.

Lifestyle and Dietary Tips While Taking Azathioprine

Stay Hydrated: Proper hydration supports liver and kidney function.
Balanced Diet: Focus on nutrient-rich foods to support your immune system.
Monitor Symptoms: If you experience unexplained bruising, infections, or fatigue, consult your doctor promptly.

Note: Azathioprine tablets are a powerful tool for managing autoimmune conditions, organ transplants, and chronic diseases. However, they require careful monitoring and guidance from a healthcare professional to minimize risks.

This guide is for informational purposes only from DengYueMed and is not a substitute for professional medical advice. Always consult your doctor before starting or changing medications.

FAQ About Azathioprine Tablets

What is the use of azathioprine tablet?

Azathioprine tablets are used to suppress the immune system, treating autoimmune diseases like rheumatoid arthritis and preventing organ transplant rejection.

Is azathioprine a high-risk drug?

Azathioprine is considered a medication that requires careful use and monitoring due to its potential for significant side effects, such as bone marrow suppression, liver toxicity, and increased susceptibility to infections.

Is azathioprine a steroid?

No, azathioprine is not a steroid. It is an immunosuppressant medication that helps reduce immune system activity and is often used alongside steroids to treat autoimmune conditions and prevent organ rejection.

Is azathioprine a chemo tablet?

Initially used as a chemotherapy drug for leukemia, azathioprine’s immunosuppressive properties later led to its use in autoimmune diseases and organ transplants.